[Lezmoe! (Oyu no Kaori)] Cross Ange no Erohon! Kanketsu Kinen ☆ Otsukare Summer Party (Cross Ange: Tenshi to Ryuu no Rondo)

and I thought at first that Cross Ange was much more of a Gen Urobuchi-written anime (although in fact Urobutcher himself is not the writer). Needless to say, the titular protagonist, according to @Luke Atemey is a strongest female main character up to date. No one could have ever survived from being brainwashed by a perverted casanova.

Agreed with Luke Atmey-san. The anime is practically bring me to tears. And joy of knowing the MC despair through out the series. Ahh . . . the sweet taste of despair, terror and other negative pronounce . . .

A very underrated anime in my opinion. And the female lead is one (if not) the strongest main character I've seen on recent anime. The first three if not four episodes will turn people off but if you could just stick with it till the end, it's well worth it. Trust me.